Mathematical Modeling and Computer Simulation in Blood Coagulation (Pathophysiology of Haemostasis and Thrombosis)
Mathematical Modeling and Computer Simulation in Blood Coagulation (Pathophysiology of Haemostasis and Thrombosis) PDF, ePub eBook D0wnl0ad
Special Topic Issue: Pathophysiology of Haemostasis and Thrombosis 2005, Vol. 34, No. 2-3 Blood coagulation, a complex system of enzymatic reactions responsible for hemostasis and thrombosis, has recently become a focus of active theoretical research. This publication is a first attempt to bring together mathematical modeling and computer simulation studies of various aspects of the coagulation system reported by leading laboratories in this field. A wide area of coagulation-related problems is considered, including control of the plasma coagulation cascade, threshold excitation of clotting, balance of coagulation and clot lysis, accuracy of deterministic and stochastic approaches to coagulation modeling, and effect of blood flow on thrombus formation. This special issue will be of interest to specialists in the biochemistry of blood coagulation, metabolic control, theoretical biology and bioinformatics. Applications of the described mathematical models and conclusions obtained can be useful in clinical practice and pharmaceutical design in hemostasis- and thrombosis-related areas.From reader reviews:
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